Antony Varghese was born in AngamalyKochiKerala, India to Varghese and Alphonsa.

He made his debut in 2017 by portraying the lead role of Vincent Pepe in Angamaly Diaries, directed by Lijo Jose Pellissery. The Film was a blockbuster hit which rose him to fame, he is now well known by his screen name in the movie, Pepe. This character took him to places and won several awards including Filmfare Awards South.[2] His second film was Swathandriam Ardharathriyil, directed by debutant Tinu Pappachan. It is a Kottayam based thriller. He has signed Jallikettu marking his second collaboration with Lijo Jose Pellissery.